Better In Vitro – In Vivo Correlation (IVIVC) has long been an industry aim. This is particularly difficult in the case of inhaled and nasal products because of the complications involved in precisely correlating drug deposition behaviour with clinical efficacy, the impact of patient-to-patient variability and the complex interaction between formulation and device.
One strategy for improving the significance of cascade impaction data is to modify the test set-up in order to mimic the in vivo drug delivery process more closely.
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29th June 2018; Nottingham, UK: New products from Copley Scientific enhance its offering for impr...
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28 May 2015; Nottingham, UK: New experimental studies using the Child Alberta Idealised Throat (C...
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5 August 2014; Nottingham, UK: The desire to gain a better understanding of how inhaled products ...
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1 December 2010; Nottingham, UK: The Alberta Idealized Throat is a new product from Copley Scient...
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The regulatory landscape for OINDPs – the biggest shake-up in a generation?...
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Optimizing the Application of In Vitro Test Methods for the Demonstration of Bioequivalence in Or...
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Demonstrating Bioequivalence of Orally Inhaled Products...
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Optimising the application of in vitro test methods for the demonstration of BE in OIPs...
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Comparison between in vitro performance of the Child “Alberta” Idealized Throat and Ph.Eur./U...
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