Breathing Simulators

Representative breathing patterns should be employed during inhaler testing that characterise the age and condition of the patients to be treated (paediatric to geriatric, mild to severe impairment of the lungs).
The Copley range of Breathing Simulators are designed to generate an inhalation and/or exhalation profile that mimics that of a human subject and have become routinely used in orally inhaled product testing to replace existing constant flow conditions with breathing profiles more representative of conditions in vivo.

BRS 3100 - Breathing Simulator

Similar in design and operation to the BRS 2100, the BRS 3100 has a larger volume of 500 mL - 5 L (certified). It also features a maximum flow rate of 240 L/min (free flow) and a maximum acceleration of 25L/s2 making it the ideal unit for the testing of MDIs and DPIs for improved IVIVCs.

BRS 3100 Features
Volume (computer-controlled):
500 mL to 5 L
0+ (upper defined by acceleration limit)
I:E Ratio:
Sinusoidal, Square, Triangular, User defined (flow vs time)
Inhalation and/or Exhalation
On inhalation or exhalation stroke User defined profiles (flow vs time)
User Interface:
Embedded computer (Windows 10)
Limited testing of Nebulisers (Ph. Eur. 2.9.44 and USP <1601> and testing MDIs with Spacers/VHCs (USP <1602> Improving IVIVCs for MDIs and DPIs: With DUSA for MDI/DPI (Dose Uniformity) With Impactor and Mixing Inlet (APSD)

Related Services


We offer a range of training courses, presentations and seminars covering a wide range of topics....

Find Out More


A comprehensive range of both in-house and on-site product servicing options are available...

Find Out More


Our team of experienced technicians and engineers are on hand to help and advise ...

Find Out More

Related News & Resources