定量吸入气雾剂(MDI)与呼吸驱动吸入气雾剂(BAI)的APSD空气动力学粒径分布

MDI或BAI的空气动力学粒径分 布将决定气溶胶微细粒子吸 入后可能的沉积位置。如果微细粒子太大, 则会卡在咽喉后部。 微细粒子太小,则被呼出而不是沉积在体内。 多级撞击器是测量MDI或BAI产品的APSD 是否满足法规和药典要求的首选仪器, 有五种不同的多级撞击器适合评估APSD, 但美国和欧洲药典只 提及了安德生多级撞击器(ACI), 新一代撞击器 (NGI) 和多级液体撞击器(MSLI)。

请选择一个冲击器:

Breath Actuation Controller BAC 100i

Breath-Actuated MDIs (BAIs)

The Breath Actuation Controller BAC 100i can also be used for the testing of Breath-Actuated (or Breath-Operated) MDIs. In this case, the BAC 100i is used to initiate the flow, simultaneously triggering the breath-actuated inhaler.

MDIs: Semi-Automated APSD Measurement

The Vertus automated shake, fire and shot waste range is made up of integrated turn-key solutions for precise, controlled and reproducible MDI testing. Compatible with most MDIs, the Vertus systems offer analysts complete control over:

  • The speed, angle and duration of shaking, ahead of actuation
  • Firing force and the speed of application and release of that force
  • The time delay between the end of shaking and device actuation
Vertus II

Related Applications

We also offer a range of equipment for additional MDI testing application support:

省工工具

提高效率
减少变异性
消除处理错误
提高试验能力

级联撞击器是怎样运作?

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