定量吸入气雾剂(MDI)空气动力学粒径分布(APSD)
MDI或BAI的空气动力学粒径分 布将决定气溶胶微细粒子吸 入后可能的沉积位置。如果微细粒子太大, 则会卡在咽喉后部。 微细粒子太小,则被呼出而不是沉积在体内。 多级撞击器是测量MDI或BAI产品的APSD 是否满足法规和药典要求的首选仪器, 有五种不同的多级撞击器适合评估APSD, 但美国和欧洲药典只 提及了安德生多级撞击器(ACI), 新一代撞击器 (NGI) 和多级液体撞击器(MSLI)。
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级联撞击器是怎样运作?
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