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Exacerbated evaporation caused by the thermal mass of the NGI may be an issue for devices such as nebulisers that deliver the drug as an aerolised solution. Loss of solvent reduces droplet size, producing artificially low particle size measurements and compromises the integrity of APSD data.
The hub of an inhaler testing system, the ITW is a modular workstation designed to aid handling and manipulation of the various pieces of test apparatus and accessories, improving workflow. The ITW offers analysts the flexibility to pick and choose the attachments necessary for their test set-up needs. Simply connect the required attachments and start testing with greater ease.
The majority of nasal products are designed to generate droplets/particles with a mass median aerodynamic diameter (MMAD) of greater than 10 to 20 microns. This is to increase nasal deposition and minimise deposition in the lungs. However, most sprays deliver a proportion (typically <5%) of fine droplets in the <10 micron range. It is important to quantify this Fine Particle Dose (FPD) since it can penetrate beyond the nasal tract and into the lower respiratory tract or lungs, which may be undesirable. Cascade impactors are designed to capture particles in the range 0 to 10 microns and are widely used for this application.
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递送剂量均一性（DDU）取样仪系列产品能够帮助准确评估释放的药物总量。
精密设计的多级撞击器系列产品可测量吸入药物的大小分布（微细粒子直径），提供有关气溶胶微细粒子吸入后，在肺中可能沉积位置的重要信息。
Copley Scientific提供一系列试验仪器，用于经口吸入制剂及鼻用制剂（OINDP）的附加鉴定和验证，包括评估仿制药制剂 ， 吸入药物溶出度试验和改善体内外相关性。
采用我们的半自动化解决方案，吸入制剂试验无需人工干预。
