We appreciate you letting us know that what makes semisolid testing different? is a key area of interest.
Semisolid and topical formulations bring a different set of characterisation challenges compared with conventional solid dosage forms. Product performance can depend not only on how the formulation releases the active ingredient, but also on how that ingredient diffuses through the formulation and permeates across a membrane or biological barrier. As a result, techniques such as dissolution, diffusion and permeation can each provide different insights into how a product is likely to behave in use.
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