DDU of Dry Powder Inhalers (DPIs)
The basic requirements for DPI DDU testing are the same as for MDI testing, namely DUSA, mouthpiece adapter, vacuum pump and flow meter. However, a critical flow controller (e.g. Critical Flow Controller TPK 100i) to measure the pressure drop across the device and control the flow conditions during testing is also required. This is because most DPIs are passive breath-actuated devices which rely on the patient’s inspiration rather than a propellant for dose aerosolisation and delivery. The testing of DPIs is further complicated by the fact that different inhalers provide varying degrees of flow resistance, i.e. some require more effort to inhale through than others.
HCP6 High Capacity Pump
View ProductTPK 100i Critical Flow Controller
View ProductInhaler Testing Workstation ITW
View ProductDose Uniformity Sampling Apparatus (DUSA) for DPIs
View BrochureDFM 2000 Flow Meter
View ProductWSC2 Waste Shot Collector
View BrochureMouthpiece Adapter
View ProductDUSA Stand for DPIs
View BrochureTemperature/Humidity Sensor
View BrochureMouthpiece Adapter Support Accessory
View BrochureDFM4 Flow Meter
View ProductSCP6 Super Capacity Pump
View ProductAPSD of Dry Powder Inhalers (DPIs)
View ProductHCP6 High Capacity Pump
View ProductTPK 100i Critical Flow Controller
View ProductInhaler Testing Workstation ITW
View ProductDose Uniformity Sampling Apparatus (DUSA) for DPIs
View BrochureDFM 2000 Flow Meter
View ProductWSC2 Waste Shot Collector
View BrochureMouthpiece Adapter
View ProductDUSA Stand for DPIs
View BrochureTemperature/Humidity Sensor
View BrochureMouthpiece Adapter Support Accessory
View BrochureDFM4 Flow Meter
View ProductSCP6 Super Capacity Pump
View ProductAPSD of Dry Powder Inhalers (DPIs)
View ProductDDU Over the Entire Contents
In the case of DPI reservoir type devices, tests should be carried out throughout the life of the inhaler i.e. dose uniformity over the entire contents.
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We also offer a range of equipment for additional MDI testing application support:
Related Applications
Two factors have been identified as being critical to improving the clinical relevance of DDU testing and APSD measurement: realistic breathing profiles and realistic throat and nasal models.
View MoreSemi-Automation Tools
Semi-Automation Tools
All of the tests involved in Delivered Dose Uniformity require the collection and drug recovery of individual doses into the collection tube of a Dosage Unit Sampling Apparatus (DUSA) appropriate to its type (MDI or DPI) prior to assay.
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