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Special Applications

Copley offers a range of testing equipment for additional qualification and validation of orally inhaled and nasal drug products (OINDPs), including assessments of generic drug formulations, inhaled dissolution testing and improving IVIVCs.

Device Robustness / Inhaler Misuse

Copley offers solutions to aid those developing inhaled drug devices and products in understanding the impact of poor patient technique on the critical quality attributes (CQAs) of inhalers to help optimise inhaler designs for more robust drug delivery.

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Patient Exhalation Simulator (PES)

Abbreviated Impactor Measurement (AIM)

The concept of Abbreviated Impactor Measurment (AIM) is founded on the basis that once the full Aerodynamic Particle Size Distribution (APSD) profile of the product has been established in development using a full-resolution cascade impactor (and the process validated) then for product batch release testing and QC applications, it is possible to use simpler but highly sensitive metrics, solely to determine if the product is fit for purpose. This is known as Efficient Data Analysis (EDA).

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USP Monographs (Generic Drug Development)

USP monographs are most commonly used for product release testing, but may also be considered during product development.

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Related Inhaler Testing Products

For further information about the other products in our inhaler testing range, please select one of the options below.

Delivered Dose Uniformity (DDU)

Our range of Delivered Dose Uniformity (DDU) sampling apparatus are designed to help accurately assess the total amount of emitted drug.

Delivered Dose Uniformity (DDU)

Ancillaries

Optimise inhaler testing workflows with our broad range of supporting equipment required to make up fully-operating test systems for Delivered Dose Uniformity (DDU) and Aerodynamic Particle Size Distribution (APSD) of orally inhaled and nasal drug products (OINDPs).

Ancillaries

Special Applications

Copley Scientific offers a range of testing equipment for additional qualification and validation of orally inhaled and nasal drug products (OINDPs), including assessments of generic drug formulations, inhaled dissolution testing and improving IVIVCs.

Special Applications

Aerodynamic Particle Size Distribution (APSD)

Our range of precision engineered cascade impactors measure the size distribution (particle size) of inhaled drug products, providing critical information about where particles in aerosol clouds are likely to be deposited in the lungs following inhalation.

Aerodynamic Particle Size Distribution (APSD)

Improving IVIVCs

Better IVIVC has long been an industry aim. This is particularly difficult in the case of inhaled and nasal products because of the complications involved in precisely correlating drug deposition behaviour with clinical efficacy, the impact of patient-to-patient variability and the complex interaction between formulation and device.