APSD of Metered Dose Inhalers (MDIs)
The APSD testing of MDIs is typically performed at a flow rate of 28.3 L/min when using an ACI or 30 L/min when using an NGI. For Breath Actuated MDIs (BAIs) a Breath Actuation Controller may also be used to generate a time delay. However, it must be noted that when add-on devices such as spacers or valved holding chambers (VHCs) are used, the APSD characteristics may be substantially altered from what is emitted when the MDI is used alone and must be assessed appropriately.
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MDIs: Semi-Automated APSD Measurement
The Vertus® III automated shake, fire and shot waste range is made up of integrated turn-key solutions for precise, controlled and reproducible MDI testing. Compatible with most MDIs, the Vertus III systems offer analysts complete control over:
- The speed, angle and duration of shaking, ahead of actuation
- Firing force and the speed of application and release of that force
- The time delay between the end of shaking and device actuation
Breath-Actuated MDIs (BAIs)
The Breath Actuation Controller BAC 100i can also be used for the testing of Breath-Actuated (or Breath-Operated) MDIs. In this case, the BAC 100i is used to initiate the flow, simultaneously triggering the breath-actuated inhaler.
Related Applications
We also offer a range of equipment for additional MDI testing application support:
Related Applications
Two factors have been identified as being critical to improving the clinical relevance of DDU testing and APSD measurement: realistic breathing profiles and realistic throat and nasal models.
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Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
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Sample Preparation Unit SPU 200i
Copley supplies a broad range of labour-saving dev…
View Product RangeAutomation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product Range
Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product Range
Automation Tools
Copley offers a range of ready-made flexible shake, fire and flow control systems for individual MDI testing with ACI, NGI, DUSA, waste shot collectors and other devices.
View Product Range
Automation Tools
Copley offers a range of ready-made flexible shake, fire and flow control systems for individual MDI testing with ACI, NGI, DUSA, waste shot collectors and other devices.
View Product Range
Automation Tools
Copley offers a range of ready-made flexible shake, fire and flow control systems for individual MDI testing with ACI, NGI, DUSA, waste shot collectors and other devices.
View Product Range
Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product Range
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