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Reliable Results Start with Controlled Drug Recovery

Manual drug recovery from impactors, DUSA collection tubes and other test components can introduce variability that impacts data quality.

The Sample Recovery Systemâ„¢ SRS 100i automates key stages of this critical step, delivering a controlled, repeatable approach to sample recovery.

With a defined, automated workflow, the system enables consistent sample preparation for DDU and APSD workflows, generating HPLC-ready samples for immediate analysis.

Patent Pending

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SRS 100i: Automated Drug Recovery in Practice

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Key Features: SRS 100i

Reproducible drug recovery across analysts and sites

Controlled solvent dispensing and dissolution

Reduced manual handling and hands-on recovery time

HPLC-ready samples for immediate analysis

Configurable to suit most laboratory workflows

Eliminates risk of cross-contamination

Aligns with established recovery methods

Designed for use in regulated environments (21 CFR Part 11 and GMP)

Drug Recovery for DDU and APSD in Four Steps

1. Load

Test components are placed are placed into dedicated holders within the system

2. Dispense

Defined volumes of solvent are delivered to each component and collection surface.

3. Dissolve

Controlled solvent delivery and rinsing support consistent recovery using established methods.

4. Collect

Prepared samples are aspirated into HPLC vials, ready for immediate analysis.

Sample Recovery System™ SRS 100i Technical Specifications

Dispensing accuracy

± 1%

Agitation Speed

10-60 RPM (±1 RPM)

Run Time

Up to 24 hours

(up to 60,000 revolutions)

Connectivity

USB A, USB B, RS 232 (run in digital input)

Dimensions (w x d x h)

590 x 320 x 235 mm

Inhalytix®+ Compatible

  • Method and operational parameters can be transferred into Inhalytix+
  • Supports unified, traceable workflows for APSD measurement
  • Reduces manual data handling and improves data consistency
  • HPLC results generated downstream can be imported into Inhalytix+ to complete the dataset

Learn more about Inhalytix+

Frequently Asked Questions: Automated Drug Recovery

Explore our most frequently asked questions about our Sample Recovery Systemâ„¢ SRS 100i and drug recovery, covering implementation, use and regulatory compliance.

Why automate drug recovery in inhaler testing?

Manual drug recovery relies on operator technique, which can introduce variability. Automated drug recovery standardises key steps, supporting controlled, repeatable execution and improving confidence in results.

How does the SRS 100i improve reproducibility?

The SRS 100i controls key variables in the recovery process, including solvent, dispensing, dissolution and sample collection. By replacing manual intervention with a defined, repeatable workflow, it delivers consistent execution across runs, analysts and sites.

Can the SRS 100i be used for DDU and APSD workflows?

Yes. The SRS 100i supports drug recovery for both Delivered Dose Uniformity (DDU) testing and Aerodynamic Particle Size Distribution (APSD) measurement, working with standard components such as DUSA systems, impactors and associated components including induction ports and preseparators.

Can the SRS 100i be used within our existing inhaler testing workflows?

The SRS 100i is designed to closely align with established manual recovery approaches. By replicating key steps within a controlled, automated workflow, it supports a straightforward transition from manual to automated methods while maintaining consistency in sample handling.

How does the system support data integrity?

By standardising solvent delivery, dissolution and sample handling, the SRS 100i reduces operator-dependent variation and supports consistent, traceable execution of recovery processes. Additionally, Inhalytix®+ compatibility enables the transfer of method parameters and operational data into a unified platform, supporting complete, traceable datasets and helping to generate robust and defensible results.

Does the SRS 100i support regulatory compliance?

The SRS 100i supports use in regulated environments by standardising key stages of the drug recovery process, including solvent dispensing, dissolution and sample handling. This controlled, repeatable approach reduces operator-dependent variation, while built-in electronic records functionality supports data integrity and traceability in line with regulatory requirements, including 21 CFR Part 11 and GMP.

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