Inhaled Dissolution

In the case of inhaled and nasal drug delivery products, once the drug is deposited to the target site, the absorption or lung uptake, and hence the therapeutic effectiveness of the drug, depends on the active dissolving in the small amounts of aqueous fluid and lung surfactant available.

NGI Dissolution Cup and Membrane Holder

Based on a concept developed by Professor Jason McConville at the College of Pharmacy, University of Texas, USA the NGI Dissolution Cup and Membrane Holder incorporates a modification of the standard NGI collection cup. It allows size-fractionated particles from an aerosol cloud to be collected and then tested in a conventional tablet dissolution tester.

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Related News & Resources

Copley Scientific launches world’s first commercial apparatus for dissolution testing of inhaled drugs

25th January 2010

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Optimizing the Application of In Vitro Test Methods for the Demonstration of Bioequivalence in Orally Inhaled Products

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Demonstrating Bioequivalence of Orally Inhaled Products

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Optimising the Application of In Vitro Test Methods for the Demonstration of BE in OIPs

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