Please select a DISi Series tester for further product information
Easy-clean Viton® membrane-sealed zero-evaporation lids included as standard
Intuitive touchscreen control with icon-based menu structure simplifies operation
Robust metal case with advanced corrosion protective coating
PT100 temperature probe monitors bath and vessel temperature with electronic calibration feature
Independent digital heater/circulator maintains a constant temperature and minimises vibration
Easily removable leak-proof water bath with convenient drain tap eases bath water emptying
All vessels are serial-numbered as standard
Convenient screw-in basket/paddles enable easy method change in seconds
Maximum fill line indicator
‘Easy-Centre’ centring system for precise vessel positioning
With bench space a premium in many laboratories, the DIS 600i is one of the most compact dissolution testers available on the market today.
Ideal for use in both R&D and QC environments, the DISi 600i is equipped with precision ground shafts that will accept any of the baskets, paddles or rotating cylinders described in the Ph. Eur., USP and associated Pharmacopoeias.
Catalogue Number: |
1336 |
Pharmacopoeial Compliance: |
Ph. Eur. 2.9.3 and 2.9.4 USP <711> and <724> |
Ph. Eur. and USP Test Methods Supported: |
1, 2, 5, 6 |
Number of Stirred Vessels: |
6 |
Heater Type: |
Low vibration independent external digital heater/circulator |
Unit Dimensions (w x d x h): |
728 x 495 x 689 mm (unit) |
Please select a DISi Series tester for further product information
Easy-clean Viton® membrane-sealed zero-evaporation lids included as standard
Intuitive touchscreen control with icon-based menu structure simplifies operation
Robust metal case with advanced corrosion protective coating
PT100 temperature probe monitors bath and vessel temperature with electronic calibration feature
Independent digital heater/circulator maintains a constant temperature and minimises vibration
‘Easy-Centre’ centring system for precise vessel positioning
Maximum fill line indicator
Convenient screw-in basket/paddles enable easy method change in seconds
All vessels are serial-numbered as standard
Easily removable leak-proof water bath with convenient drain tap eases bath water emptying
Maximising visibility and access to the critical sampling area above the bath, the DIS 800i represents the very latest in tablet testing technology.
Ideal for use in both R&D and QC environments, the DISi 800i is equipped with precision ground shafts that will accept any of the baskets, paddles or rotating cylinders described in the Ph. Eur., USP and associated Pharmacopoeias.
Catalogue Number: |
1338 |
Pharmacopoeial Compliance: |
Ph. Eur. 2.9.3 and 2.9.4 USP <711> and <724> |
Eur. Ph & USP Test Methods Supported: |
1, 2, 5, 6 |
Number of Stirred Vessels: |
8 |
Heater Type: |
Low vibration independent external digital heater/circulator |
Unit Dimensions (w x d x h): |
728 x 495 x 689 mm (without heater) 260 x 330 x 150 mm (heater) |
Ph. Eur. and USP compliant
Integrated, precision temperature control and measurement
Intuitive touchscreen control to simplify operation
Single-point electronic temperature calibration
Six and eight test station unit configurations available
Extensive data reporting output options: RS 232, USB A and USB B
Wide speed range to accommodate broad scope of methods
Option to automate and remotely control DISi Series systems
All the DISi series are equipped with precision-ground shafts that will accept any of the baskets, paddles or rotating cylinders described in the Pharmacopoeias. Individual clutches enable each individual basket/paddle to be raised/lowered or engaged independently of the drive head making the series suitable for staggered starts, whilst also ensuring maximum user accessibility.
Compliant with USP/Eur. Ph. specifications, all DISi Series vessels feature unique Easy-Centre systems ensuring perfect positioning every time. UV-resistant vessels are also available. Easy-clean Viton® membrane-sealed low evaporation lids are included as standard with each vessel.
With dimensional tolerances a factor of 2 higher than those specified in the FDA Enhanced Calibration, the EMC Ultra Precision Dissolution Vessel brings even higher levels of accuracy to dissolution testing.
Eliminate the need for time-lag correction factor calculations with the Automatic Tablet Drop system. Guaranteeing simultaneous tablet ejection at the start of the test run, synchronised sampling is simplified.
We offer a range of dissolution sampling probe systems, designed for different user requirements, including manual sample processes, as well as automated sampling.
Formulated to produce reproducible results under standard dissolution test conditions, these standard drug references supplied by USP (Rockville, Maryland, USA) can be used to help verify the source of anomalies.
Copley offers equipment for three different methods for the determination of the rate of drug release from transdermal patches:
Based on the same principles as the Rotating Disk apparatus as described in USP Chapter <1087>, Copley offers punch and die kits, together with a hand operated press for intrinsic dissolution methods.
For dosage forms with small quantities, or extended release where much lower concentrations are required than that provided by the standard 1000 mL vessel, 100 mL and 200 mL conversion kits are available.
For solid dosage forms that have a tendency to block the standard 40 mesh basket, a basket with a coarser mesh is available to retain the dosage form in the basket, whilst allowing media penetration without clogging.
With the same basic basket specification as the USP standard, the special suppository basket provides the equivalent porosity to a basket of 10 mesh, allowing suppository dissolution testing to take place unimpeded.
In the case of inhaled and nasal drug delivery products, once the drug is deposited to the target site, the absorption or lung uptake, and hence the therapeutic effectiveness of the drug, depends on the active dissolving in the small amounts of aqueous fluid and lung surfactant available.
