A Comparison of the Effect of Continuous Cooling of an NGI on a Solution and Suspension Based Nebulised Products
Research indicates that as a nebulised plume passes through an NGI, heat transfer from the impactor causes evaporation of the nebulised solution, resulting in an inaccurate distribution of particles. It has been suggested that cooling the NGI will help to reduce this evaporation,
Currently there are limited data that consider this issue with respect to different nebuliser formulations and how different methods for cooling the impactor affect performance of the test.
This study was performed to look at the effects of temperature on aerodynamic particle size of both solutions and suspension formulations and to consider the effect of continuous cooling throughout nebulisation versus ‘a fridge method’.
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