27 June 2023; Nottingham, UK: The new Flow Rate Sensor FRS is the latest addition to Copley Scientific’s orally inhaled and nasal drug product (OINDP) testing portfolio which sets the benchmark for innovative, efficient, and reliable inhaler testing solutions. The FRS is a robust, low resistance, bi-directional flow sensor that delivers rapid data output via a direct interface with a suitable flow controller, streamlining operation and maintaining a reduced test set-up footprint. A product of Copley’s engineering excellence, and designed specifically for inhaler testing, it offers exemplary flow rate measurement for compendial-compliant testing and allows users to accurately track complex inhalation profiles.
Compendial methods for OINDPs specify the setting of representative flow rates for both delivered dose uniformity testing (DDU) and aerodynamic particle size distribution (APSD) by cascade impaction. Accurate control is especially important for APSD measurement since cascade impactor performance is calibrated as a function of air flow rate. Beyond compendial methods, assessing the impact of inhalation profile characteristics such as rise-time is increasingly common practice as developers work to enhance product performance for specific patient populations.
The FRS is an easy-to-use device that integrates seamlessly into standard test set-ups to provide consistent and accurate flow measurement for all types of OINDPs including dry powder inhalers, metered dose inhalers, aqueous droplet inhalers, nebulisers, nasal sprays, and nasal powders. Key features include:
- Simple, robust design specified for integration, control, and display via the Breath Actuation Controller BAC 100i or Critical Flow Controller TPK 100i
- Bi-directional flow functionality for flexible installation
- Rapid data output for in-depth analysis
- Low flow resistance for high flow testing with minimal impact
Find out more about the new FRS and how it enhances your OINDP test set-up here.
The new Flow Rate Sensor FRS from Copley: a dedicated low resistance flow sensor for your inhaler test set-up.
About Copley Scientific
Copley Scientific is widely recognised as the world’s leading manufacturer and supplier of inhaler test equipment and is a major provider of testing systems for other pharmaceutical dosage forms. The company also supplies equipment for detergent testing.
Copley’s pharmaceutical product range includes test equipment for all types of orally inhaled and nasal drug products – metered-dose inhalers, dry powder inhalers, nebulisers and nasal sprays – with a particular focus on solutions for delivered dose uniformity and aerodynamic particle size distribution measurement. It also includes testers for tablets (dissolution, disintegration, friability and hardness) capsules, powders, suppositories, semisolids and transdermals.
Used from R&D through to QC, this extensive range of equipment is supported by a full validation and aftersales service. Copley works in partnership with specialist distributors, extending localised support across the world. This network provides expert help and training to every customer, directly enhancing the application of all Copley products. www.copleyscientific.com