A previous EPAG cross-industry study investigated flow rate-rise time profiles with full resolution CIs at target flow rates of 30, 60 and 90 L/min and with orifice plates representative of high-, medium-, and low-resistance DPIs. The study goal was to quantify how such differences may affect characteristic flow rate-rise time profiles.
Jolyon Mitchell1, Daryl Roberts2, Henk Versteeg3, Andy Cooper4, Mark Copley5, Roland Greguletz6
Presented at Drug Delivery to the Lungs (DDL) 2022, Edinburgh, UK.
1 Jolyon Mitchell Inhaler Consulting Services Inc., 1154 St. Anthony Road, London, N6H 2R1, Canada
2 Applied Particle Principles LLC, 17347 Westham Estates Court, Hamilton, VA 20158, USA
3 Mechanical and Manufacturing Engineering, Loughborough University, Loughborough, LE11 3TU, UK.
4 Kindeva Drug Delivery, Derby Road, Loughborough, LE11 5SF, UK
5 Copley Scientific Ltd., ColwickQuays Business Park, Rd. No 2, Colwick, Nottingham NG4 2JY, UK
6 Sofotec GmbH, a member of the AstraZeneca Group, Benzstraße1-3, Bad Homburg, D-61352, Germany
