The BRS 100i is specifically designed for generating neonatal, infant, child and adult breathing patterns required for dose uniformity testing of nebulisers in accordance with ISO 27427:2013. It can also be used to generate the profiles required in USP <1602> for testing ‘Spacers and Valve Holding Chambers used with Inhalation Aerosols’.
Ph. Eur. 2.9.44, USP <1601>, <1602> and ISO 27427:2013 compliant
Intuitive, touchscreen user interface
Extensive data output options
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BRS 100i Technical Specifications
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Volume (manually adjust):
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0 to 800 mL
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Frequency:
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12 - 40 bpm
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I:E ratio:
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1:1, 1:2 or 1:3
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Waveforms:
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Sinusoidal
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Patient profile suitability:
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Neonate/Infant, Child, Adult
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Profile:
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Inhalation and Exhalation
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Start:
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Select start on inhalation or exhalation stroke
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User interface:
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Touchscreen
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Uses:
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Testing Nebulisers (Ph. Eur. 2.9.44 and USP <1601>
Testing MDIs with Spacers/VHCs (USP <1602>
Improving IVIVCs for MDIs with Spacers/VHCs and nebulisers:
With Filter Holder and Adapter (Dose Uniformity)
With Impactor and Mixing Inlet (APSD)
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The BRS 100i can also be used in place of a standard vacuum pump with a cascade impactor such as the NGI or ACI and a Mixing Inlet to form a simple and inexpensive system for APSD studies utilising more representative patient profiles for MDIs with and without a spacer/VHC.
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