Breathing Simulators
From the generation of simple sinusoidal patterns as stated in the Ph. Eur. and USP for testing nebulisers and MDIs with a spacer/VHC, to complex user-generated profiles for improving in-vitro in-vivo correlations (IVIVCs), our range of Breathing Simulators can be used across a variety of testing applications and patient physiologies.
Contact Us
Contact Us
BRS 200i Breathing Simulator
The BRS 200i is a breathing simulator with up to 900 mL volume suitable for the testing of Nebulisers and MDIs with Spacers and Valve Holding Chambers (VHCs). Specifically designed to generate all of the breathing profiles used to measure the drug delivery rate and tidal drug delivered of nebulisers according to Ph. Eur. 2.9.44 and USP <1601> and MDIs used with a spacer/VHC as per USP <1602>, the BRS 200i is also suitable for generating other wave forms in studies to improve IVIVCs.
21 CFR Part 11 compliant
Stores and recalls methods
Improved accuracy for infant and neonate profile volume requirements
Extensive data output options
Seamless integration with the Vertus® III range for automated shake, fire, and flow control in breath profile testing
Enhanced features including automatic data backups and report printing for greater efficiency and reliability
|
BRS 200i Features
|
|
|---|---|
|
Volume:
|
0 to 900 mL
|
|
Frequency:
|
6 – 60 bpm
|
|
I:E ratio:
|
Variable
|
|
Waveforms:
|
Sinusoidal, Square, Triangular, User-defined (flow vs time)
|
|
Profile:
|
Inhalation and/or Exhalation
|
|
Start:
|
On inhalation or exhalation stroke / User-defined profiles (flow vs time)
|
|
User interface:
|
Touchscreen
|
|
Uses:
|
Testing Nebulisers (Ph. Eur. 2.9.44) and USP <1601> Testing MDIs with Spacers/VHCs (USP <1602> | Improving IVIVCs for MDIs with Spacers/VHCs and nebulisers: With Filter Holder and Adapter (Dose Uniformity) With Impactor and Mixing Inlet (APSD)
|
BRS 200i User Interface
- BRS 200i user log-in screen
- Pre-defined breathing pattern method selection
- Customisation and creation of breathing pattern methods
- Main run test screen (ready to test)
Related Accessories
NGI Cooler Stand
The NGI Cooler Stand supports the interfacing of the NGI Cooler with the BRS 200i, whilst saving precious benchtop space.
View Brochure
NGI Cooler Stand
The NGI Cooler Stand supports the interfacing of the NGI Cooler with the BRS 200i, whilst saving precious benchtop space.
Real-Time Breath Verification Chamber
Enables measurement and recording of the breathing profile generated through the inhaler during the actual test itself, using the Breath Profile Analyser BPA available in the Qualification Kit for BRSi Series (Cat. No. 9115) required. For use with the USP Induction Port only.
View Brochure
Real-Time Breath Verification Chamber
Enables measurement and recording of the breathing profile generated through the inhaler during the actual test itself, using the Breath Profile Analyser BPA available in the Qualification Kit for BRSi Series (Cat. No. 9115) required. For use with the USP Induction Port only.
Related Services
Training
We offer a range of training courses, presentations and seminars covering a wide range of topics.
Find Out More
Servicing
A comprehensive range of both in-house and on-site product servicing options are available
Find Out More
Support
Our team of experienced technicians and engineers are on hand to help and advise
Find Out MoreRelated News & Resources
