DDU of Aqueous Droplet Inhalers (ADIs)
Both MDIs and DPIs suffer from the same two inherent problems: low lung deposits (typically 5-20%) and dose variability (often due to patient difficulties in coordination or inspiration). Aqueous Droplet Inhalers (often known as “Solution Metering” or “Soft Mist” Inhalers), are a new generation of inhaler designed to overcome these problems. Since they are active, aqueous-based devices, the DDU testing of ADIs is similar to that of MDIs, with testing carried out at a constant flow rate of 28.3 L/min.
Low Capacity Pump LCP6
View ProductBreath Actuation Controller BAC 100i
View ProductInhaler Testing Workstation ITW
View ProductDose Uniformity Sample Apparatus (DUSA) for MDIs
View BrochureFlow Rate Sensor FRS
View ProductWaste Shot Collector WSC2
View BrochureMouthpiece Adapter
View ProductEnviroMate™ – Benchtop Environmental Chamber
View ProductFlow Meter DFM 2000
View ProductDUSA Stand for DPIs
View BrochureTemperature/Humidity Sensor
View BrochureLabel Printer
View BrochureAPSD of Aqueous Droplet Inhalers (ADIs)
View SystemLow Capacity Pump LCP6
View ProductBreath Actuation Controller BAC 100i
View ProductInhaler Testing Workstation ITW
View ProductDose Uniformity Sample Apparatus (DUSA) for MDIs
View BrochureFlow Rate Sensor FRS
View ProductWaste Shot Collector WSC2
View BrochureMouthpiece Adapter
View ProductEnviroMate™ – Benchtop Environmental Chamber
View ProductFlow Meter DFM 2000
View ProductDUSA Stand for DPIs
View BrochureTemperature/Humidity Sensor
View BrochureLabel Printer
View BrochureAPSD of Aqueous Droplet Inhalers (ADIs)
View SystemDDU Over the Entire Contents
In the case of multiple dose devices, tests might need to be carried out throughout the life of the inhaler i.e. dose uniformity over the entire contents.
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We also offer a range of equipment for additional MDI testing application support:
Related Applications
Two factors have been identified as being critical to improving the clinical relevance of DDU testing and APSD measurement: realistic breathing profiles and realistic throat and nasal models.
View MoreSemi-Automation Tools
Semi-Automation Tools
All of the tests involved in Delivered Dose Uniformity require the collection and drug recovery of individual doses into the collection tube of a Dosage Unit Sampling Apparatus (DUSA) appropriate to its type (MDI or DPI) prior to assay.
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