Cascade Impactor Metrics: Exploring New Guidance on Data Analysis

In this article, Dr Clair Brooks, Applications Specialist, examines the parameters used to quantify and compare the aerodynamic particle size distribution metrics of orally inhaled drug products and methods for calculation, including those laid out in the new USP <1604>, with reference to both “standard” and efficient data analysis metrics to elucidate current debate and establish sufficient understanding for the effective day-to-day application of these methods.