APSD of Dry Powder Inhalers (DPIs)
The APSD measurement of Dry Powder Inhalers is typically performed under the same conditions as DDU testing, however a Preseparator is typically interposed between the induction port and stage 0 of cascade impactor to capture the large, non-inhalable carrier particles, to prevent impactor over-loading (when using an NGI or ACI). As for delivered dose dry powder inhaler testing, test flow rate is set on the basis of a 4 kPa pressure drop across the device, to approximate the mean patient inhalation flow rate achieved during clinical use.
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NGI Preseparator
For the collection of large mass, non-inhalable powder blouses typically emitted from a DPI prior to entry into the impactor, to prevent impactor over-loading.
- High capacity
- High efficiency
- Two-stage separation
- Sharp and reproducible cut-point between 10-15 microns (depending on flow rate)
Induction Port P1 Measurement Adapter
Used together with the Critical Flow Controller, the Induction Port P1 Measurement Adapter can be placed between the inhaler and the induction port to measure the pressure drop (P1) over the inhaler under test in the absence of a DUSA for DPIs.
View BrochureRelated Applications
We also offer a range of equipment for additional DPI testing application support:
Related Applications
Two factors have been identified as being critical to improving the clinical relevance of DDU testing and APSD measurement: realistic breathing profiles and realistic throat and nasal models.
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Automation Tools
Improve efficiency
Reduce variability
Eliminate handling error
Increase testing capacity Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
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Sample Preparation Unit SPU 200i
Copley supplies a broad range of labour-saving dev…
View Product RangeAutomation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product Range
Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product Range
Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product Range
How Does a Cascade Impactor Work?
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