APSD of Nasal Products
Nasal drug products typically produce droplets larger than 10-20 microns, to ensure nasal deposition and minimise deposition within the lungs. However, a proportion of fine droplets in the <10 micron range may also be produced. Deposition of this respirable fraction beyond the nasal tract may be undesirable and must be quantified. Aerodynamic particle sizing with a cascade impactor is a US FDA requirement and is recommended in USP <601> to assess potential deposition beyond the nasal cavity.
Our nasal product testing solutions enable better, more informative testing in line with evolving market requirements.
Nosepiece Adapter
View ProductUSP Induction Port
View BrochureAndersen Cascade Impactor ACI
View BrochureInhaler Testing Workstation ITW
View ProductTPK 100i Critical Flow Controller
View ProductFlow Rate Sensor FRS
View ProductHCP6 High Capacity Vacuum Pump
View ProductTemperature and Relative Humidity Sensor
View BrochureDFM 2000 Flow Meter
View ProductFootswitch
View BrochureNGI Cup Rack
View BrochureNGI Carrying/Washing Rack
View BrochureLabel Printer
View BrochureDDU of Nasal Products
View SystemNosepiece Adapter
View ProductUSP Induction Port
View BrochureAndersen Cascade Impactor ACI
View BrochureInhaler Testing Workstation ITW
View ProductTPK 100i Critical Flow Controller
View ProductFlow Rate Sensor FRS
View ProductHCP6 High Capacity Vacuum Pump
View ProductTemperature and Relative Humidity Sensor
View BrochureDFM 2000 Flow Meter
View ProductFootswitch
View BrochureNGI Cup Rack
View BrochureNGI Carrying/Washing Rack
View BrochureLabel Printer
View BrochureDDU of Nasal Products
View SystemThe angle of the impactor can be adjusted to replicate the angle that the nasal powder device may be used at to investigate device performance under representative conditions. The APSD measurement is unaffected by gravimetric forces.
Related Applications
We also offer a range of equipment for additional nebuliser testing application support:
Related Applications
Two factors have been identified as being critical to improving the clinical relevance of DDU testing and APSD measurement: realistic breathing profiles and realistic throat and nasal models.
View MoreSemi-Automation Tools
Semi-Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product RangeSemi-Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product RangeSemi-Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product RangeSample Preparation Unit SPU 200i
Copley supplies a broad range of labour-saving dev…
View Product RangeSemi-Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product RangeSemi-Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product RangeHow Does a Cascade Impactor Work?
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Find Out MoreRelated News & Resources
Copley introduces the new Flow Rate Sensor, a dedicated device for inhaler testing systems.
27th June 2023
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Introducing the Copley Impactor Genie™ IG 200i, a two-in-one solution for quicker, more efficient inhaled product testing
25th April 2023
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Copley launches EnviroMate™, an efficient, benchtop environmental chamber for inhaler testing
14th September 2022
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Copley Scientific joins the Industries Forum of the Taskforce for Lung Health
22nd June 2021
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Introducing Inhalytix®: a new solution for analysing and managing inhaler test data from Copley
18th March 2021
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Nasal Product Testing Brochure 2023
View download
Understanding the Links Between Drug Delivery Route and In Vitro Test Methods
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Nasal Drug Product Development
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Reducing Inhaler Testing Variability Through Test Environment Control
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Improving In Vitro Test Methods for Nasal Drug Products
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Semi-Automating Inhaler Testing – A Good Idea, but Where to Start?
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A short Q&A with our CEO, Mark Copley, On Inhaled Product Testing
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