Automated Shake, Fire and Flow Control for MDIs, Nasal Sprays and Aerosols

Vertus® III is a fully-automated shake and fire benchtop system for precision-controlled, highly repeatable MDI, nasal spray and nasal aerosol testing. Compatible with most MDI and nasal device types and a wide range of collection devices, offering total control over the test technique, but the flexibility to apply any industry-standard test method.

Shake parameter control ensures the required motion is achieved. It is precisely controlled, completely configurable and repeatable.

Firing can be configured to apply up to three distinct forces per actuation. These are typically used to set forces that detect, insert and fire the canister.

Precision Control

Suitable for testing MDIs, nasal sprays and nasal aerosols. Each device is clipped securely into a holder.

Interchangeable interface plates make switching between collection devices quick and simple.

Large, modern and intuitive touchscreen on adjustable arm for greater accessibility.

Vertus® III

Offering precisely controlled and repeatable delivery for Delivered Dose Uniformity (DDU) testing and Aerodynamic Particle Size Distribution (APSD) measurement, automating all aspects of MDI, nasal spray and nasal aerosol dose sampling.

Compatible with over 40 different collection device combinations including DUSA, Next Generation Impactor (NGI), Alberta Idealised Throat and Nasal Inlets, and Spray Force Tester, the Vertus III range offers total control over the test technique, but the flexibility to apply any industry-standard shake and fire test method.

Key Features: Vertus® III

Ph. Eur., EMA, USP, FDA, ChP and NMPA compliant

21 CFR part 11 compliant

Precise control over all test parameters

Suitable for a wide range of devices

Compatible with all standard collection devices

In situ impactor leak testing capability

Wide range of data output options

Precision-controlled, highly repeatable MDI, nasal spray and nasal aerosol testing

Vertus® III offers absolute control over a wide range of specific method parameters, including:

  • Shaking profile (including speed, angle and duration)
  • Time between shake and fire
  • Firing profile (including force, pause, fire down, rise and release time)
  • Air flow through system

The Vertus® III Range – Automated Shake and Fire Systems for MDIs and Nasal Sprays

Play Video

NEW: Priming & Waste Module

Included as standard, the new Priming & Waste Module integrates firing-to-waste into automated test methods, enabling compendial entire contents testing with minimal manual input.

Each interface plate can be placed directly on top of the Priming & Waste Module. Vertus III and Vertus III+ can switch automatically between priming and test levels, firing-to-waste or to dose collection as required, without operator intervention. This enables highly efficient testing procedures, most notably to meet through-life test requirements for DDU and APSD.

Exhaust Port Vertus

NEW: Exhaust Port

The Exhaust Port supports the efficient extraction of flammable propellants or high potency drugs where additional safety measures are required, for example, as part of pMDI reformulation studies.

Vertus® III: Interface Plates

All Vertus® III interface plates are interchangeable, meaning analysts can easily swap between collection devices. No tools are required, simply lift and switch!

Over 40 collection device combinations are available, a selection of which are shown below. For a full list of all available interface plates, contact us at sales@copleyscientific.co.uk.

DUSA Stack with Priming & Waste Module

DUSA Interface Plate for Nasal Sprays

Next Generation Impactor NGI with Priming & Waste Module

Andersen Cascade Impactor ACI with Glass Expansion Chamber

Andersen Cascade Impactor ACI with Adult Alberta Idealised Throat and Priming & Waste Module

Next Generation Impactor NGI with Alberta Idealised Nasal Inlet AINI

Spray Force Tester SFT

Thin Layer Chromatography TLC Plate for Spray Pattern

Method Transfer: DecaVertus® III

Vertus® III is fully compatible with DecaVertus® III. Therefore methods can be easily transferred between systems as the product proceeds to commercialisation, with DecaVertus used in production to alleviate the burden of MDI through-life testing.

Find Out More: DecaVertus® III

Vertus III®: Technical Specifications

Device compatibility:

Metered Dose Inhalers (MDIs), Nasal Sprays, Nasal Aerosols

Shot weight measurement:

No

Static Eliminator included:

No

Dimensions (w x d x h):

1020 x 510 x 920 mm

Related Services

Related News & Resources

New, automated shake and fire platforms from Copley cut the burden of MDI and nasal drug product testing.

7th November 2023

Find out more

New accessory completes Copley’s solution for automated nasal drug product testing

26th October 2021

Find out more

Copley Scientific joins the Industries Forum of the Taskforce for Lung Health

22nd June 2021

Find out more

Copley introduces a comprehensive range for nasal product testing

11th March 2021

Find out more

Copley Scientific acquires automation experts Novi Systems

11th April 2019

Find out more

Nasal Product Testing Brochure 2023 (2 mb)

View download

Perfect Timing for the Automation of OINDP Testing

View download

Nasal Drug Product Development

View download

Investigating the Impact of Electrostatics on Delivered Dose Uniformity for pMDIs

View download

Improving In Vitro Test Methods for Nasal Drug Products

View download

Refining Test Methods for a New Generation of Nasal Drug Products

View download

Semi-Automating Inhaler Testing – A Good Idea, but Where to Start?

View download

Putting Inhalers to the Test

View download

A short Q&A with our CEO, Mark Copley, On Inhaled Product Testing

View download

Optimizing the Role of Automation in Variability Reduction Strategies For Delivered Dose Uniformity (DDU) and Aerodynamic Particle Size Distribution (APSD) Testing of Inhaled Drug Products

View download

A New, Advanced High-Throughput System for Automated Inhaler Testing

View download