DDU of Nasal Products
Recent developments in nasal delivery systems has resulted in greater focus on different uses for drug delivery. With great potential for rapid drug absorption into the turbinates and lymphoid tissues located at the back of the nasal cavity, focus has shifted to absorption into the systemic circulation and central nervous system for a wider range of treatments.
Our nasal aerosol testing solutions enable better, more informative testing in line with evolving market requirements.
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DUSA Interface Plate for Nasal Aerosols
Simplifying the measurement of delivered dose uniformity testing for nasal sprays in accordance with the European Pharmacopoeia (Ph. Eur.) Chapter 0676 and United States Pharmacopoeia (USP) Chapter <601>, the nasal dose uniformity sampling apparatus (DUSA) interface plate enables simple, leak-free connection between a standard DUSA and the nasal drug product to ensure complete dose capture. Designed for use with the Vertus® III/III+ automated shake and fire system, routine test set-ups for nasal drug products are now easily automated using our complete integrated solution.
- Apparatus as specified in USP Chapter <601> and Ph.Eur. 0676
- Automated nasal spray shaking (Vertus® III/+)
- Automated nasal spray actuation (Vertus® III/+)
- Automated flow control (Vertus® III/+)
- Automated shot weight measurement (Vertus® III+)
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Nasal Spray Dose Collector (NSDC)
Specially designed for nasal spray DDU testing, the NSDC has an optimised internal geometry to eliminate splashback, drips and leakage following actuation to ensure complete spray dose capture every time.
Designed for use with the Vertus® III/+ automated shake and fire systems, the NSDC enables reproducible and time efficient nasal spray testing. It can also be used as a standalone device for the manual dose collection of nasal sprays.
Nasal Spray Waste Collector (NSWC)
Streamlining nasal spray wasting, the NSWC is designed to collect high volumes of waste aerosol doses with no splashback onto the nozzle for safe and convenient disposal of waste drug product.
Designed for use with the Vertus® III/+ automated shake and fire systems, the NSWC improves the speed and efficiency of nasal spray wasting.
Vertus® III Range – Automated Shake and Fire Systems for MDIs, Nasal Sprays and Nasal Aerosols
Semi-Automation Tools
Improve efficiency
Reduce variability
Eliminate handling errors
Increase testing capacity Semi-Automation Tools
All of the tests involved in Delivered Dose Uniformity require the collection and drug recovery of individual doses into the collection tube of a Dosage Unit Sampling Apparatus (DUSA) appropriate to its type (MDI or DPI) prior to assay.
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