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DDU of Nasal Products

Recent developments in nasal delivery systems has resulted in greater focus on different uses for drug delivery. With great potential for rapid drug absorption into the turbinates and lymphoid tissues located at the back of the nasal cavity, focus has shifted to absorption into the systemic circulation and central nervous system for a wider range of treatments.

Our nasal aerosol testing solutions enable better, more informative testing in line with evolving market requirements.

Nasal Sprays

Nasal Aerosols

Nasal Powders

Nasal Sprays

Nasal Aerosols

Nasal Powders

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Dose Uniformity Sampling Apparatus (DUSA) Nasal Spray Dose Collector (NSDC) and Nasal Spray Waste Collector (NSWC)

DUSA Interface Plate for Nasal Aerosols

Simplifying the measurement of delivered dose uniformity testing in accordance with the European Pharmacopoeia (Ph. Eur.) Chapter 0676 and United States Pharmacopoeia (USP) Chapter <601>, the nasal dose uniformity sampling apparatus (DUSA) interface plate enables simple, leak-free connection between a standard DUSA and the nasal drug product to ensure complete dose capture. Designed for use with the Vertus® II/Plus automated shake and fire system, routine test set-ups for nasal drug products are now easily automated using our complete integrated solution.

Apparatus as specified in USP Chapter <601> and Ph.Eur. 0676
Automated nasal aerosol shaking (Vertus® III/+)
Automated nasal aerosol actuation (Vertus® III/+)
Automated flow control (Vertus® III/+)
Automated shot weight measurement (Vertus® III+)
Can be used with NSWC for waste dose collection during DDU over entire contents testing

Please select an option:

Dose Uniformity Sampling Apparatus (DUSA) Nasal Spray Dose Collector (NSDC) and Nasal Spray Waste Collector (NSWC)

Nasal Spray Dose Collector (NSDC)

Specially designed for nasal spray DDU testing, the NSDC has an optimised internal geometry to eliminate splashback, drips and leakage following actuation to ensure complete aerosol dose capture every time.

Designed for use with the Vertus® II/Plus automated shake and fire systems, the NSDC enables reproducible and time efficient nasal aerosol testing. It can also be used as a standalone device for the manual dose collection of nasal sprays.

Nasal Spray Dose Collector (NSDC)

Streamlining nasal spray wasting, the NSDC is designed to collect high volumes of waste aerosol doses with no splashback onto the nozzle for safe and convenient disposal of waste drug product.

Designed for use with the Vertus® II/Plus automated shake and fire systems, the NSDC improves the speed and efficiency of nasal spray wasting.

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Vertus® III Range – Automated Shake and Fire Systems for MDIs, Nasal Sprays and Nasal Aerosols

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Semi-Automation Tools

Improve efficiency

Reduce variability

Eliminate handling errors

Increase testing capacity

Semi-Automation Tools

All of the tests involved in Delivered Dose Uniformity require the collection and drug recovery of individual doses into the collection tube of a Dosage Unit Sampling Apparatus (DUSA) appropriate to its type (MDI or DPI) prior to assay.