Automated Shake, Fire and Flow Control for MDIs, Nasal Sprays and Aerosols

Vertus® Plus is a fully automated benchtop shake and fire system for precision-controlled, highly repeatable MDI, nasal spray and nasal aerosol testing, with integral shot weight measurement.

Automatic Weighing. An integrated 4 or 5-place Mettler Toledo analytical balance is used to collect shot weight data at any point of the method.

The device is securely clipped into a holder, which in turn is clipped onto the Vertus. This allows most styles of device to be supported without the need to remove the canister from the device.

Shaking is performed using closed loop control, which assures that the required motion is achieved. It is precisely controlled, completely configurable and repeatable.

Firing can be configured to apply up to three distinct forces per actuation. These are typically used to set forces that detect, insert and fire the canister.

Precision Control

Optional: External printer

Vertus® Plus

Vertus Plus offers all the functionality of Vertus II, but in addition has an integrated 5 decimal place weighing balance which automatically records the mass of the MDI or nasal device at any point during a method.

With Vertus Plus, even complex methods requiring shot weight collection can be fully automated, to the point of push button, walkaway operation, freeing analysts for more productive tasks, while at the same time, boosting data integrity.

Key Features: Vertus® Plus

Ph. Eur. and USP compliant

21 CFR part 11 compliant

Ideal for both R&D and QC applications

In situ impactor leak testing capability

Compatible with a range of collection devices, including DUSA, NGI and waste shot collectors.

Wide range of data output options

Precision-controlled, highly repeatable MDI, nasal spray and nasal aerosol testing

Vertus PlusVertus® offers absolute control over a wide range of specific method parameters, including:

  • Shaking profile (including speed, angle and duration)
  • Time between shake and fire
  • Firing profile (including force, pause, fire down, rise and release time)
  • Air flow through system

The Vertus® Series – Automated Shake and Fire Systems for MDIs and Nasal Sprays

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Vertus® Plus Interface Plates

All Vertus® interface plates are interchangeable, meaning analysts can easily swap between collection devices. No tools are required, simply lift and switch!

Photos of some of the interface plates available are shown below. For a full list of available interface plates, contact us at sales@copleyscientific.co.uk.

DUSA Stack with Waste Shot Collector Interface Plate

DUSA Interface Plate for Nasal Sprays

Next Generation Impactor NGI Interface Plate

Next Generation Impactor NGI with Glass Expansion Chamber

Andersen Cascade Impactor ACI Interface Plate

Andersen Cascade Impactor ACI with Alberta Idealised Nasal Inlet (AINI)

Method Transfer: DecaVertus® II

Both Vertus® II/Plus are fully compatible with DecaVertus® II. Therefore methods can be easily transferred between systems as the product proceeds to commercialisation, with DecaVertus often used in production to alleviate the burden of inhaler through-life testing.

Find Out More: DecaVertus®

Static Eliminator

Are electrostatic charges causing issues for your testing? Designed for use with the Vertus® II/Plus, our Static Eliminator has been shown to be effective in eliminating the unwanted variability that static introduces. Contact us to find out how the Static Eliminator can help with your testing.

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Vertus® Plus: Optional Extras

The optional features provide additional convenience and further functions to measure and record regulatory approved test methods as required by a particular application.

  • Internal airflow generation with automatic control and measurement
  • Automatic leak test to measure equipment integrity
  • Monitor and record of temperature and relative humidity
  • ER/ES compliance functionality
  • LIMS link so that results can results can be stored directly to a central information management system
  • DUSA Stack: a combined 4-DUSA & waste shot collector device for unattended high throughput operation with shot weights automatically recorded
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