APSD of Metered Dose Inhalers (MDIs)

The APSD testing of MDIs is typically performed at a flow rate of 28.3 L/min when using an ACI or 30 L/min when using an NGI. For Breath Actuated MDIs (BAIs) a Breath Actuation Controller may also be used to generate a time delay. However, it must be noted that when add-on devices such as spacers or valved holding chambers (VHCs) are used, the APSD characteristics may be substantially altered from what is emitted when the MDI is used alone and must be assessed appropriately.

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Vertus III with DUSA Stack and Priming& Waste Module

MDIs: Semi-Automated APSD Measurement

The Vertus® III automated shake, fire and shot waste range is made up of integrated turn-key solutions for precise, controlled and reproducible MDI testing. Compatible with most MDIs, the Vertus III systems offer analysts complete control over:

  • The speed, angle and duration of shaking, ahead of actuation
  • Firing force and the speed of application and release of that force
  • The time delay between the end of shaking and device actuation
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Breath-Actuated MDIs (BAIs)

The Breath Actuation Controller BAC 100i can also be used for the testing of Breath-Actuated (or Breath-Operated) MDIs. In this case, the BAC 100i is used to initiate the flow, simultaneously triggering the breath-actuated inhaler.

Semi-Automation Tools

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