APSD of Soft Mist Inhalers (SMIs)
For SMIs as for nebulisers, the evaporation of droplets exacerbated by the thermal mass of the impactor can be a problem. Loss of solvent reduces droplet size, producing artificially low APSD measurements, compromising the integrity of the resulting data. Cooling the impactor to approximately 5°C is the recommended method for overcoming this problem. Classified as active devices, the recommended flow rate for ADI testing is 28.3 L/min for the ACI or 30 L/min for the NGI.
Mouthpiece Adapter
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View BrochureACI Collection Plate Rack
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View BrochureDDU of Aqueous Droplet Inhalers (ADIs)
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View BrochureNGI Induction Port
View BrochureAndersen Cascade Impactor ACI
View BrochureBAC 100i Breath Actuation Controller
View BrochureLCP6 Low Capacity Vacuum Pump
View BrochureFlow Rate Sensor FRS
View BrochureNGI Cooler
View BrochureInhalytix® – APSD Data Analysis Software
View BrochureTemperature and Relative Humidity Sensor
View BrochureFlow Meter DFM 2000
View BrochureFootswitch
View BrochureQuick Clamp
View BrochureACI Collection Plate Rack
View BrochureNGI Carrying/Washing Rack
View BrochureDDU of Aqueous Droplet Inhalers (ADIs)
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We also offer a range of equipment for additional ADI support:
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Two factors have been identified as being critical to improving the clinical relevance of DDU testing and APSD measurement: realistic breathing profiles and realistic throat and nasal models.
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Semi-Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product RangeSample Preparation Unit SPU 200i
Copley supplies a broad range of labour-saving dev…
View Product RangeSemi-Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product RangeHow Does a Cascade Impactor Work?
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Find Out MoreRelated News & Resources
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Copley’s appointment of new Applications Specialist, Clair Brooks, highlights commitment to exemplary customer support.
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Introducing the Copley Impactor Genie™ IG 200i, a two-in-one solution for quicker, more efficient inhaled product testing
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Copley launches a new semi-automation tool for inhaled product testing
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Copley Scientific joins the Industries Forum of the Taskforce for Lung Health
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Introducing Inhalytix®: a new solution for analysing and managing inhaler test data from Copley
18th March 2021
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Copley announces a major upgrade of the world’s ‘go to’ inhaler testing portfolio
1st March 2021
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Confused about cascade impaction? Watch the new animations from Copley Scientific to improve your understanding of inhaled drug product testing.
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New maintenance tools from Copley Scientific help optimise inhaler testing
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New, state-of-the-art vision system central to Copley Scientific’s cascade impactor validation service
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Understanding the Links Between Drug Delivery Route and In Vitro Test Methods
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Reducing Inhaler Testing Variability Through Test Environment Control
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Semi-Automating Inhaler Testing – A Good Idea, but Where to Start?
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Putting Inhalers to the Test
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A short Q&A with our CEO, Mark Copley, On Inhaled Product Testing
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Semi-Automation in Inhaler Testing – Exploring the Potential and Practicalities
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The Regulatory Landscape for OINDPs – The Biggest Shake-up in A Generation?
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Optimizing the Application of In Vitro Test Methods for the Demonstration of Bioequivalence in Orally Inhaled Products
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Demonstrating Bioequivalence of Orally Inhaled Products
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Optimising the Application of In Vitro Test Methods for the Demonstration of BE in OIPs
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