Home > Inhaler Testing > Aerodynamic Particle Size Distribution (APSD) > APSD of Nebulisers > ASPD of Nebulisers
APSD of Nebulisers
For devices such as nebulisers, the evaporation of droplets exacerbated by the thermal mass of the impactor can be a problem, especially for drugs in solution. Loss of solvent reduces droplet size, producing artificially low APSD measurements, compromising the integrity of the resulting data. Cooling the impactor to approximately 5°C is the recommended method for overcoming this problem. The recommended flow rate of 15 L/min employed in the APSD testing of nebulisers is lower than that of other OINDPs in order to better represent the tidal breathing conditions employed in their use.
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View BrochureBAC 100i Breath Actuation Controller
View ProductLCP6 Low Capacity Vacuum Pump
View ProductFlow Rate Sensor FRS
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View ProductInhalytix® – APSD Data Analysis Software
View ProductEnviroMate™ – Benchtop Environmental Chamber
View ProductTemperature and Relative Humidity Sensor
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View BrochureDFM 2000 Flow Meter
View ProductHCP6 High Capacity Vacuum Pump
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We also offer a range of equipment for additional nebuliser testing application support:
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Two factors have been identified as being critical to improving the clinical relevance of DDU testing and APSD measurement: realistic breathing profiles and realistic throat and nasal models.
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One of the main factors influencing the amount of inhaled drug available to the patient is the interface between the facemask and the patient. Investigating and defining the effect of a facemask to the product’s DDU and APSD is important for the product development.
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Semi-Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
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Copley supplies a broad range of labour-saving dev…
View Product RangeSemi-Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product RangeSemi-Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product RangeSemi-Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
View Product RangeSemi-Automation Tools
Copley supplies a broad range of labour-saving devices and semi-automated systems for Aerodynamic Particle Size Distribution applications.
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