DDU of Nasal Products

Vertus® for Nasal Spray Testing

Designed for use with the Vertus II/Plus automated shake and fire system, routine test set-ups with the NSDC and NSWC are easily automated using our complete integrated solution:

• Apparatus as specified in USP Chapter <601> and Ph.Eur. 0676
• Automated nasal spray shaking (Vertus® III/+)
• Automated nasal spray actuation (Vertus® III/+)
• Automated flow control (Vertus® III/+)
• Automated shot weight measurement (Vertus® III+)

Shake. Fire. Weigh. Repeat.

The Vertus® III+ model has the additional feature of a 5-decimal place balance for automated nasal spray shot weight measurement. Automatically recording the mass of the inhaler at any point during a method, the Vertus Plus conveniently reports shot weight data along with all other test information.

Nasal Spray Dose Collector NSDC

Specially designed for the DDU testing of nasal sprays, the NSDC works together with the Vertus II/Plus automated actuation systems, but it can also be used as a standalone device for the manual dose collection of nasal sprays.

• The drug is sprayed into an opening large enough to guarantee no drug hits the entrance but is small enough to greatly reduce the risk of drug exiting after actuation.
• The ‘shark’s fin’ design deflects the spray away from the centre point of the nozzle in an aerodynamic fashion to minimise the risk of any rebound.
• All points on the fin itself slope away from the centre point thereby encouraging any drips that form to run away from the centre.

Manual Nasal Spray Testing

The Nasal Spray Dose Collector (NSDC) can also be used as a standalone device for the manual dose collection of nasal sprays.